SCHEMBL16553554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17943738	0.94	NR1H2 (0.71)	NR1H2MARS1MDM2MCL1BCL2
	SCHEMBL29496569	0.89	NR1H2 (0.73)	NR1H2MARS1RXRANR1H3PTGS2
	SCHEMBL16566131	0.89	NR1H2 (0.73)	NR1H2MARS1RXRANR1H3PTGS2
	SCHEMBL16566090	0.87	NR1H2 (1.00)	NR1H2RXRANR1H3PTGS2
	SCHEMBL16566124	0.87	NR1H2 (0.70)	NR1H2RXRANR1H3SLC16A3SLC16A1
	SCHEMBL29496560	0.87	NR1H2 (0.70)	NR1H2RXRANR1H3SLC16A3SLC16A1
	SCHEMBL17970790	0.86	NR1H2 (0.72)	NR1H2RXRANR1H3PTGS2
	SCHEMBL16553481	0.86	NR1H2 (0.58)	NR1H2MARS1MDM2MCL1BCL2
	SCHEMBL25878810	0.85	NR1H2 (0.68)	NR1H2RXRANR1H3PTGS2
	SCHEMBL16553546	0.84	NR1H2 (0.67)	NR1H2RXRANR1H3PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.