SCHEMBL16554268

SCHEMBL16554268

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CBr)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.41
NPY1R P25929 10/20 0.41
NPY5R Q15761 9/20 0.41
NPY2R P49146 6/20 0.41
QRFPR Q96P65 1/20 0.39
C3AR1 Q16581 1/20 0.38
NOD1 Q9Y239 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8721756 0.95 C3AR1 (0.41) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL9453833 0.92 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RC3AR1
SCHEMBL3961387 0.89 QRFPR (0.46) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL3961412 0.89 QRFPR (0.46) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL29569172 0.89 QRFPR (0.46) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL30193290 0.88 QRFPR (0.45) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL16553852 0.88 QRFPR (0.40) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL543973 0.87 C3AR1 (0.44) NPY4RNPY1RNPY5RNPY2RC3AR1
SCHEMBL29435094 0.85 SLC15A2 (0.45) NPY4RNPY1RNPY5RNPY2RQRFPR
SCHEMBL29568549 0.84 NPY4R (0.47) NPY4RNPY1RNPY5RNPY2RC3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10155793-B2 Modified bacterial collagen-like proteins COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2018-12-18 US disclosed
US-20160376326-A1 MODIFIED BACTERIAL COLLAGEN-LIKE PROTEINS EVONIK OPERATIONS GMBH (DE) 2016-12-29 US disclosed
EP-3044233-A1 MODIFIED BACTERIAL COLLAGEN-LIKE PROTEINS Commonwealth and Scientific And Industrial Research Organisation (AU) 2016-07-20 EP disclosed
WO-2015031950-A1 MODIFIED BACTERIAL COLLAGEN-LIKE PROTEINS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2015-03-12 WO disclosed