O-Tolylamine

O-Tolylamine

SCHEMBL1655431

Cc1ccccc1N.O=P(O)(O)Oc1c[nH]c2ccc(Br)c(Cl)c12

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.37
HTR1A P08908 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Tolylamine SCHEMBL29750547 1.00 HTR2A (0.37) HTR2AHTR1AHTR2CHTR2BCYP3A4
O-Tolylamine SCHEMBL4096509 1.00 HTR2A (0.37) HTR2AHTR1AHTR2CHTR2BCYP3A4
O-Tolylamine SCHEMBL7116171 0.90 HTR2A (0.32) HTR2AHTR1AHTR2CHTR2B
SCHEMBL23488 0.86 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
SCHEMBL29356973 0.86 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
SCHEMBL17668115 0.84 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
Ammonia Solution, Strong SCHEMBL20492883 0.84 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
SCHEMBL5058499 0.84 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
SCHEMBL31324009 0.84 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2
Phosphoric Acid SCHEMBL8156858 0.84 HTR2A (0.40) HTR2AHTR1AHTR2CHTR2BNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5149623-A Dot enzyme immunoassay; colorimetric analysis VIROTEST, INC. (US) 1992-09-22 US claimed
EP-0438457-A1 A METHOD FOR SIMULTANEOUS DETECTION OF DIFFERENT TYPES OF ANTIBODIES AND/OR ANTIGENS PRODUCED BY INDIVIDUAL CELLS SYNTELLO AB (SE) 1991-07-31 EP claimed
WO-1990004182-A1 A METHOD FOR SIMULTANEOUS DETECTION OF DIFFERENT TYPES OF ANTIBODIES AND/OR ANTIGENS PRODUCED BY INDIVIDUAL CELLS VIROVAHL S.A. (CH) 1990-04-19 WO claimed
JP-63137698-A None JP disclosed
WO-2023177181-A1 MEDIUM COMPOSITION FOR CULTURING PORCINE PLURIPOTENT STEM CELLS 주식회사 스페이스에프 2023-09-21 WO disclosed
CN-114689837-A Culture related to antigen sensitization state associated with transplantation of capillary endothelial cells, use thereof, and detection kit comprising same 沃复生(苏州)医学检验所有限公司 2022-07-01 CN disclosed
EP-3704226-A1 METHOD FOR THE IN VITRO PREPARATION OF DERMAL PAPILLA AND HAIR FOLLICLE EQUIVALENTS L'Oreal (FR) 2020-09-09 EP disclosed
EP-2483695-A2 ABNORMAL ALTERATIONS OF PKC ISOZYMES PROCESSING IN ALZHEIMER'S DISEASE PERIPHERAL CELLS Blanchette Rockefeller Neurosciences, Institute (US) 2012-08-08 EP disclosed
US-20110212474-A1 ABNORMAL ALTERATIONS OF PKC ISOZYMES PROCESSING IN ALZHEIMER'S DISEASE PERIPHERAL CELLS BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE (US) 2011-09-01 US disclosed
WO-2011041670-A2 ABNORMAL ALTERATIONS OF PKC ISOZYMES PROCESSING IN ALZHEIMER'S DISEASE PERIPHERAL CELLS BLANCHETTE ROCKEFELLER NEUROSCIENCES INSTITUTE (US) 2011-04-07 WO disclosed
US-7572926-B2 Plant seed oil of a rapeseed plant having endogenous saturated fatty acids comprising from 22.9% to 26.3% stearate; compositions and methods of use of plant desaturase enzymes, especially Delta -9 desaturases, are provided; use in genetic engineering of plants CALGENE, INC. (US) 2009-08-11 US disclosed
US-5093230-A Method for rapid and sensitive detection of IgM retroviral antibodies VERIGEN, INC. (US) 1992-03-03 US disclosed
EP-0469045-A1 SYNTHETIC -i(PSEUDOMONAS) -i(AERUGINOSA) PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS. UNIV ALBERTA (CA) 1992-02-05 EP disclosed
WO-1991013972-A1 PLANT DESATURASES - COMPOSITIONS AND USES CALGENE, INC. (US) 1991-09-19 WO disclosed
EP-0438457-A1 A METHOD FOR SIMULTANEOUS DETECTION OF DIFFERENT TYPES OF ANTIBODIES AND/OR ANTIGENS PRODUCED BY INDIVIDUAL CELLS SYNTELLO AB (SE) 1991-07-31 EP disclosed
WO-1990013563-A1 SYNTHETIC PSEUDOMONAS AERUGINOSA PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 1990-11-15 WO disclosed
WO-1990004182-A1 A METHOD FOR SIMULTANEOUS DETECTION OF DIFFERENT TYPES OF ANTIBODIES AND/OR ANTIGENS PRODUCED BY INDIVIDUAL CELLS VIROVAHL S.A. (CH) 1990-04-19 WO disclosed
EP-0324849-A1 Method for rapid and sensitive detection of IgM antibodies to retroviral antigens VERIGEN, INC. (US) 1989-07-26 EP disclosed
WO-1989000609-A1 METHOD FOR RAPID AND SENSITIVE DETECTION OF IgM RETROVIRAL ANTIBODIES BIO-RESEARCH LABORATORIES, INC. (US) 1989-01-26 WO disclosed
JP-S63137698-A ANALYTICAL ELEMENT FOR MEASURING ALKALINE PHOSPHATASE KONICA CORP 1988-06-09 JP disclosed