SCHEMBL16554351

SCHEMBL16554351

COc1ncc(C(=O)O)cc1-c1ccc(F)cc1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSA P10619 13/20 0.55
MAP4K4 O95819 2/20 0.49
BCL2L1 Q07817 1/20 0.45
BAD Q92934 1/20 0.45
SQOR Q9Y6N5 2/20 0.44
CNR1 P21554 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16554974 0.86 CTSA (0.56) CTSAMAP4K4CNR1
SCHEMBL30791383 0.86 CTSA (0.56) CTSAMAP4K4CNR1
SCHEMBL16554418 0.85 MAP4K4 (0.52) CTSAMAP4K4CNR1
SCHEMBL2260511 0.85 CNR1 (0.47) CTSAMAP4K4BCL2L1BADCNR1
SCHEMBL16554363 0.82 CTSA (0.57) CTSAMAP4K4CNR1
SCHEMBL2704405 0.79 CNR1 (0.66) MAP4K4CNR1
SCHEMBL20021961 0.79 CNR1 (0.54) MAP4K4CNR1
SCHEMBL16554435 0.78 CTSA (0.52) CTSACNR1
SCHEMBL2701888 0.78 MAP4K4 (0.52) CTSAMAP4K4BCL2L1BAD
SCHEMBL16554924 0.77 CTSA (0.51) CTSACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015034271-A1 NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2015-03-12 WO disclosed