Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554610 | 1.00 | CNR2 (1.00) | CNR2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL16554450 | 1.00 | CNR2 (1.00) | CNR2KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL16554727 | 0.88 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16554731 | 0.88 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16555005 | 0.88 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16554959 | 0.87 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16554976 | 0.87 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16554965 | 0.87 | CNR2 (1.00) | CNR2 | |
| SCHEMBL14911410 | 0.83 | CNR2 (0.79) | CNR2KDM4EALDH1A1 | |
| SCHEMBL14911412 | 0.83 | CNR2 (0.79) | CNR2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041843-A1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-07-13 | — | — | EP | claimed |
| WO-2015032769-A1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-03-12 | — | — | WO | claimed |
| EP-3041843-A1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015032769-A1 | NOVEL TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-03-12 | — | — | WO | disclosed |