Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 14/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179961 | 1.00 | ATM (0.44) | ATMCTSCKDM4EALDH1A1CHRNB2 | |
| SCHEMBL8291499 | 1.00 | ATM (0.44) | ATMCTSCKDM4EALDH1A1CHRNB2 | |
| SCHEMBL29952931 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL6479236 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL12437619 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL4040707 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL993042 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL21151866 | 0.80 | SLC1A2 (0.42) | ATMCTSC | |
| SCHEMBL22020094 | 0.80 | CTSC (0.40) | ATMCTSC | |
| SCHEMBL6480162 | 0.80 | SLC1A2 (0.42) | ATMCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015032942-A1 | N-SUBSTITUTED 3,3'-(BIPHENYL-4,4'-DIYL)BIS-2-AMINOPROPANENITRILES AS DPPI INHIBITORS | PROZYMEX A/S (DK) | 2015-03-12 | — | — | WO | disclosed |