SCHEMBL16558374

SCHEMBL16558374

c1ccc(-c2ccc3c(-c4ccc5c6c(cccc46)Oc4ccccc4-5)c4cc(-c5ccccc5)ccc4c(-c4ccc5c6c(cccc46)Oc4ccccc4-5)c3c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44
ELANE P08246 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 2/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
XBP1 P17861 1/20 0.33
PTBP1 P26599 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
SMAD3 P84022 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558373 1.00 ATM (0.44) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL16558379 0.99 ATM (0.43) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL16558358 0.99 ATM (0.43) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL16558386 0.99 ATM (0.43) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL16558360 0.99 ATM (0.43) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL16558380 0.91 KDM4E (0.49) ATMKDM4EMAPK1GPR84
SCHEMBL16558368 0.91 KDM4E (0.49) ATMKDM4EMAPK1GPR84
SCHEMBL23758559 0.91 ATM (0.43) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL23109612 0.90 ATM (0.45) ATMKDM4EMAPK1ELANEMEN1
SCHEMBL23109643 0.90 KDM4E (0.47) ATMKDM4EMAPK1ELANEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed