SCHEMBL16558385

SCHEMBL16558385

c1ccc2c(c1)Oc1ccc(-c3c4ccc(-c5cccc6ccccc56)cc4c(-c4ccc5c(c4)Oc4cccc6cccc-5c46)c4ccc(-c5cccc6ccccc56)cc34)c3cccc-2c13

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
MAPK1 P28482 1/20 0.48
ATM Q13315 1/20 0.48
TYMS P04818 1/20 0.33
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558364 1.00 KDM4E (0.48) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558375 0.99 KDM4E (0.49) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558384 0.99 KDM4E (0.49) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558363 0.93 MAPK1 (0.48) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558370 0.93 MAPK1 (0.48) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558383 0.93 MAPK1 (0.48) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558388 0.93 MAPK1 (0.48) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL23758616 0.92 MAPK1 (0.49) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558390 0.92 MAPK1 (0.49) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558372 0.92 MAPK1 (0.49) KDM4EMAPK1ATMTYMSMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed