SCHEMBL16558394

SCHEMBL16558394

c1ccc(-c2c3ccc(-c4ccc5c6c(cccc46)Oc4ccccc4-5)cc3c(-c3ccccc3)c3ccc(-c4ccc5c(c4)Oc4cccc6cccc-5c46)cc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
TYMS P04818 1/20 0.35
MCL1 Q07820 1/20 0.31
ACMSD Q8TDX5 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558391 0.99 KDM4E (0.49) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558393 0.93 MAPK1 (0.54) KDM4EMAPK1ATMTYMS
SCHEMBL16558380 0.92 KDM4E (0.49) KDM4EMAPK1ATMTYMSCA12
SCHEMBL16558368 0.92 KDM4E (0.49) KDM4EMAPK1ATMTYMSCA12
SCHEMBL16558399 0.92 MAPK1 (0.51) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558387 0.92 KDM4E (0.44) KDM4EMAPK1ATMMCL1ACMSD
SCHEMBL16558357 0.91 KDM4E (0.48) KDM4EMAPK1ATMTYMS
SCHEMBL16558381 0.91 KDM4E (0.48) KDM4EMAPK1ATMTYMS
SCHEMBL16558404 0.91 KDM4E (0.50) KDM4EMAPK1ATMTYMSMCL1
SCHEMBL16558392 0.91 MAPK1 (0.43) KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-9601700-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-03-21 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed
US-20150069344-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-03-12 US disclosed