SCHEMBL1657002

SCHEMBL1657002

C=CC(=O)OC(C)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 1/20 0.36
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CA14 Q9ULX7 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
MAPK1 P28482 1/20 0.32
CA12 O43570 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16433327 0.83 TSHR (0.47) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL6513306 0.82 HCAR2 (0.48) TSHRSMN1; SMN2CA14KEAP1NFE2L2
SCHEMBL25056796 0.81 TSHR (0.45) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL14586207 0.81 TSHR (0.50) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL4673026 0.80 SMN1; SMN2 (0.38) TSHRSMN1; SMN2CA14KEAP1NFE2L2
SCHEMBL11556027 0.80 HCAR2 (0.46) TSHRSMN1; SMN2CA14KEAP1NFE2L2
SCHEMBL5665734 0.79 TSHR (0.46) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL1655986 0.79 TSHR (0.48) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL19046763 0.79 TSHR (0.44) TSHRSMN1; SMN2HPGDALDH1A1TP53
SCHEMBL14586214 0.79 TSHR (0.44) TSHRSMN1; SMN2HPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7932305-B2 Viscous α-cyanoacrylate compositions ETHICON, INC. (US) 2011-04-26 US claimed
US-20090326095-A1 Viscous alpha-Cyanoacrylate Compositions ETHICON, INC. 2009-12-31 US claimed
WO-2009158302-A2 VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2009-12-30 WO claimed
EP-4303276-A1 ANTIFOULING COATING MATERIAL COMPOSITION Nitto Kasei Co., Ltd. (JP) 2024-01-10 EP disclosed
EP-4098709-B1 ANTI-FOULING COATING MATERIAL COMPOSITION NITTO KASEI CO LTD (JP) 2023-10-04 EP disclosed
EP-4098709-A1 ANTI-FOULING COATING MATERIAL COMPOSITION Nitto Kasei Co., Ltd. (JP) 2022-12-07 EP disclosed
EP-3845617-B1 ANTI-FOULING COATING MATERIAL COMPOSITION NITTO KASEI CO LTD (JP) 2022-10-05 EP disclosed
EP-3845617-A1 ANTI-FOULING COATING MATERIAL COMPOSITION Nitto Kasei Co., Ltd. (JP) 2021-07-07 EP disclosed
CN-105408299-B Pass through the method for the esterification continuous production light acrylate of thick ester level acrylic acid 阿肯马法国公司 2018-04-24 CN disclosed
CN-106467680-A Fluorescent dye dispersion, spontaneous emission Photosensitve resin composition and preparation method, color conversion filter device and the display device including it 东友精细化工有限公司 2017-03-01 CN disclosed
CN-104245761-B Process for production of acrylic acid or its derivatives 宝洁公司 2017-02-22 CN disclosed
CN-105408299-A Method for continuous production of light acrylates by esterification of a raw ester-grade acrylic acid ARKEMA FRANCE 2016-03-16 CN disclosed
US-7932305-B2 Viscous α-cyanoacrylate compositions ETHICON, INC. (US) 2011-04-26 US disclosed
US-20090326095-A1 Viscous alpha-Cyanoacrylate Compositions ETHICON, INC. 2009-12-31 US disclosed
WO-2009158302-A2 VISCOUS ALPHA-CYANOACRYLATE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2009-12-30 WO disclosed
CN-1092635-C Recovery of noble light products in distillation residues obtd. during manufacture of acrylic acid or its ester ATOCHEM ELF SA (FR) 2002-10-16 CN disclosed
US-5734075-A THERMAL CRACKING PERFORMED IN ABSENCE OF CATALYSTS ON MIXTURE OF HEAVY DISTILLATION RESIDUES; LIGHT FRACTION VAPORIZED AND DISTILLED TO RECOVER LIGHT NOBLE PRODUCTS ELF ATOCHEM S.A. (FR) 1998-03-31 US disclosed
CN-1140162-A Recovery of noble light products in distillation residues obtd. during manufacture of acrylic acid or its ester ATOCHEM ELF SA (FR) 1997-01-15 CN disclosed
CN-1132753-A Organosilicon compounds containing (meth) acryloxy groups, their preparation and their use WACKER CHEMIE GMBH (DE) 1996-10-09 CN disclosed