Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 9/20 | 0.52 |
| ▸ | WEE1 | P30291 | 2/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 4/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 2/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16571108 | 0.92 | STAT6 (0.48) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL17958750 | 0.88 | STAT6 (0.53) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16570040 | 0.88 | STAT6 (0.53) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL17958809 | 0.87 | STAT6 (0.51) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16580878 | 0.87 | STAT6 (0.51) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16569916 | 0.86 | STAT6 (0.51) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16580723 | 0.86 | STAT6 (0.51) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16570999 | 0.86 | STAT6 (0.51) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16571177 | 0.85 | STAT6 (0.49) | STAT6WEE1FGFR4FGFR1FGFR2 | |
| SCHEMBL16570362 | 0.85 | STAT6 (0.49) | STAT6WEE1FGFR4FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |