Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.48 |
| ▸ | CCND3 | P30281 | 10/20 | 0.48 |
| ▸ | JAK2 | O60674 | 7/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | JAK1 | P23458 | 2/20 | 0.48 |
| ▸ | TYK2 | P29597 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16580780 | 0.87 | PTK2 (0.48) | JAK2HDAC6HDAC1JAK1TYK2 | |
| SCHEMBL16570256 | 0.84 | PTK2 (0.48) | JAK2HDAC6HDAC1JAK1TYK2 | |
| SCHEMBL16580858 | 0.83 | PTK2 (0.45) | JAK2HDAC6TYK2JAK3PTK2 | |
| SCHEMBL16581005 | 0.83 | PTK2 (0.51) | JAK2TYK2JAK3PTK2PTK2B | |
| SCHEMBL16570232 | 0.83 | PTK2 (0.50) | JAK2TYK2JAK3PTK2PTK2B | |
| SCHEMBL16570555 | 0.82 | PTK2 (0.62) | JAK2JAK1TYK2JAK3PTK2 | |
| SCHEMBL16570503 | 0.80 | PTK2 (0.51) | JAK2TYK2JAK3PTK2AURKA | |
| SCHEMBL16570345 | 0.79 | JAK2 (0.54) | CDK4JAK2JAK3PTK2AURKA | |
| SCHEMBL16571273 | 0.78 | JAK2 (0.44) | JAK2JAK1JAK3PTK2PTK2B | |
| SCHEMBL16570299 | 0.78 | JAK2 (0.64) | CDK4JAK2JAK3PTK2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | CDK4 243/4885CCND3 1198/4885JAK2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.