Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.36 |
| ▸ | HK1 | P19367 | 2/20 | 0.34 |
| ▸ | HK2 | P52789 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19764252 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL28637106 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL17822565 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL5983168 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL1842898 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL18082320 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL1842894 | 1.00 | SMYD2 (0.36) | SMYD2HK1HK2ALOX15ADORA1 | |
| SCHEMBL8670998 | 0.99 | SMYD2 (0.35) | SMYD2HK1HK2ALOX15SLC6A2 | |
| SCHEMBL8671003 | 0.99 | SMYD2 (0.35) | SMYD2HK1HK2ALOX15SLC6A2 | |
| SCHEMBL5449704 | 0.93 | SMYD2 (0.38) | SMYD2ADORA1SLC6A2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015038596-A1 | NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2015-03-19 | — | — | WO | disclosed |