Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164697 | 0.87 | NAMPT (0.78) | NAMPT | |
| SCHEMBL15311086 | 0.87 | NAMPT (0.70) | NAMPT | |
| SCHEMBL166633 | 0.85 | NAMPT (0.75) | NAMPT | |
| SCHEMBL22402280 | 0.84 | NAMPT (0.79) | NAMPT | |
| SCHEMBL15316700 | 0.83 | NAMPT (0.81) | NAMPT | |
| SCHEMBL164407 | 0.83 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29635876 | 0.83 | NAMPT (1.00) | NAMPT | |
| SCHEMBL165218 | 0.82 | NAMPT (1.00) | NAMPT | |
| SCHEMBL17727636 | 0.82 | NAMPT (0.76) | NAMPT | |
| SCHEMBL162000 | 0.81 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611777-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL]AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031196-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL] AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |