Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579598 | 0.91 | F2R (0.81) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL486312 | 0.88 | F2R (0.75) | F2RKMT2A | |
| SCHEMBL663332 | 0.86 | F2R (1.00) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL10240200 | 0.85 | F2R (0.71) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL10242051 | 0.85 | F2R (0.79) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL485924 | 0.84 | F2R (0.64) | F2R | |
| SCHEMBL485984 | 0.84 | F2R (0.69) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL661768 | 0.82 | F2R (0.82) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL640707 | 0.82 | F2R (0.60) | F2RNPC1RAB9AMAPTSTAT1 | |
| SCHEMBL486020 | 0.82 | F2R (0.61) | F2RNPC1RAB9AMAPTSTAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183773-A1 | Substituted piperidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-02 | — | — | US | disclosed |
| US-8987248-B2 | Substituted piperidines as Par-1 antagonists | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| CN-102438985-B | Substituted piperidines as par-1 antagonists | BAYER SCHERING PHARMA AG | 2014-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183773-A1 | Substituted piperidines | VHL, PIR, PIGO | F2R 1243/4885NPC1 168/4885RAB9A 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.