Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 8/20 | 0.59 |
| ▸ | CDK4 | P11802 | 5/20 | 0.47 |
| ▸ | CCND1 | P24385 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | BRD2 | P25440 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16580724 | 0.85 | STAT6 (0.57) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16580996 | 0.85 | STAT6 (0.61) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16580961 | 0.84 | CCND3 (0.54) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16570465 | 0.82 | STAT6 (0.53) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16570901 | 0.80 | STAT6 (0.63) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16571340 | 0.79 | STAT6 (0.62) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16570197 | 0.79 | STAT6 (0.64) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16570812 | 0.79 | STAT6 (0.59) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16580932 | 0.79 | STAT6 (0.59) | STAT6CDK4CCND1CDK2CCNA2 | |
| SCHEMBL16571272 | 0.78 | STAT6 (0.55) | STAT6CDK4CCND1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |