Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.66 |
| ▸ | HTR2B | P41595 | 7/20 | 0.66 |
| ▸ | HTR2A | P28223 | 5/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591400 | 1.00 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL19262079 | 1.00 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL16585037 | 1.00 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL16569276 | 0.79 | HTR2C (0.41) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL15255153 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL19262111 | 0.79 | HTR2C (0.63) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL14708135 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL16591246 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL21503512 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL16590511 | 0.79 | HTR2C (0.66) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738642-B2 | Triazolopyridine ether derivatives and their use in neurological and pyschiatric disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-22 | — | — | US | disclosed |
| US-20160237081-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3046922-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | Bristol-Myers Squibb Company (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042243-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237081-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | GRM2, GRIK2, GRIA2 | HTR2C 34/4885HTR2B 145/4885HTR2A 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.