Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585928 | 0.86 | KDM4E (0.33) | KDM4ETP53CYP2A6CYP1A2USP8 | |
| SCHEMBL643635 | 0.76 | CA1 (0.42) | KDM4ECYP2A6MAOAMAOBIMPDH2 | |
| SCHEMBL5749242 | 0.73 | CA1 (0.40) | CYP2A6MAOBIMPDH2IMPDH1 | |
| SCHEMBL19176615 | 0.72 | CYP2A6 (0.50) | KDM4ETP53CYP2A6CYP1A2MAOA | |
| SCHEMBL21812156 | 0.67 | CA1 (0.38) | KDM4ETP53CYP2A6MIFIMPDH2 | |
| SCHEMBL2772625 | 0.65 | MIF (0.37) | KDM4EMIFP4HB | |
| SCHEMBL5828010 | 0.65 | CYP1A2 (0.44) | CYP2A6CYP1A2 | |
| SCHEMBL19919236 | 0.64 | MIF (0.36) | KDM4ETP53CYP2A6CYP1A2GRM5 | |
| SCHEMBL2768407 | 0.64 | MEN1 (0.42) | GRM5MIF | |
| SCHEMBL12316913 | 0.64 | PTPN11 (0.41) | MIFP4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040141-A1 | CYCLOBUTYLCARBOXAMIDES AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-26 | — | — | WO | disclosed |