Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.50 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072385 | 0.85 | KMT2A (0.49) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL14341086 | 0.79 | PDE10A (0.93) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL14341084 | 0.79 | PDE10A (0.79) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2125225 | 0.79 | PDE10A (1.00) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6858227 | 0.77 | PDE10A (0.96) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL27610987 | 0.77 | PDE10A (0.96) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL30999690 | 0.77 | PDE10A (0.96) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL12970154 | 0.76 | PDE10A (0.74) | PDE10AALDH1A1KMT2AMEN1MBNL1 | |
| SCHEMBL28853907 | 0.76 | PDE10A (0.74) | PDE10AALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL16585914 | 0.76 | PDE10A (0.74) | PDE10AALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040425-A1 | RESORCINOL N-ARYL AMIDE COMPOUNDS, FOR USE AS PYRUVATE DEHYDROGENASE KINASE INHIBITORS | VERNALIS (R&D) LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |