Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 17/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 17/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 17/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16587792 | 1.00 | PIM1 (0.39) | PIM1PIM3PIM2KDM4EALDH1A1 | |
| SCHEMBL3223805 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL3223798 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL4127523 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL16588145 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL15535854 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL2839933 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL13421846 | 0.84 | PIM1 (0.35) | PIM1PIM3PIM2 | |
| SCHEMBL16587821 | 0.82 | PIM1 (0.42) | PIM1PIM3PIM2KDM4EALDH1A1 | |
| SCHEMBL16587817 | 0.82 | PIM1 (0.42) | PIM1PIM3PIM2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987457-B2 | Ring-substituted N-pyridinyl amides as kinase inhibitors | NOVARTIS AG (CH) | 2015-03-24 | — | — | US | disclosed |