SCHEMBL16587796 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	PIM1	P11309	13/20	0.37

▸	PIM3	Q86V86	13/20	0.37

▸	PIM2	Q9P1W9	13/20	0.37

▸	ALDH1A1	P00352	2/20	0.37

▸	HTT	P42858	2/20	0.36

▸	GAA	P10253	1/20	0.36

▸	RAB9A	P51151	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18931645	0.84	PIM2 (0.42)	MEN1KMT2APIM1PIM3PIM2
SCHEMBL16588098	0.82	BRS3 (0.36)	MEN1KMT2APIM1PIM3PIM2
SCHEMBL793501	0.79	MEN1 (0.51)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902749	0.77	MEN1 (0.36)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902763	0.77	MEN1 (0.34)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902757	0.77	MEN1 (0.34)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902765	0.77	MEN1 (0.34)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902758	0.77	MEN1 (0.34)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL14902747	0.77	MEN1 (0.36)	MEN1KMT2AALDH1A1HTTGAA
SCHEMBL1911116	0.73	MEN1 (0.36)	MEN1KMT2AALDH1A1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8987457-B2	Ring-substituted N-pyridinyl amides as kinase inhibitors	NOVARTIS AG (CH)	2015-03-24	—	—	US	disclosed