Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 19/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 18/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 18/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15589002 | 1.00 | PIM1 (0.36) | PIM1PIM3PIM2GPR119 | |
| SCHEMBL15588817 | 0.89 | PIM1 (0.41) | PIM1PIM3PIM2GPR119 | |
| SCHEMBL15588818 | 0.89 | PIM1 (0.41) | PIM1PIM3PIM2GPR119 | |
| SCHEMBL15589000 | 0.88 | PIM1 (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL15589065 | 0.88 | PIM1 (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL15589067 | 0.88 | PIM1 (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL15588999 | 0.88 | PIM1 (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL15838639 | 0.88 | PIM1 (0.35) | PIM1PIM3PIM2GPR119 | |
| SCHEMBL15588721 | 0.88 | PIM1 (0.46) | PIM1PIM3PIM2GPR119 | |
| SCHEMBL15588718 | 0.87 | PIM2 (0.47) | PIM1PIM3PIM2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987457-B2 | Ring-substituted N-pyridinyl amides as kinase inhibitors | NOVARTIS AG (CH) | 2015-03-24 | — | — | US | disclosed |