Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12632771 | 0.92 | MEN1 (0.53) | MEN1KMT2AASAH1PRSS1CTSG | |
| SCHEMBL15281661 | 0.92 | MEN1 (0.53) | MEN1KMT2AASAH1PRSS1CTSG | |
| SCHEMBL15281660 | 0.92 | MEN1 (0.50) | MEN1KMT2AASAH1PRSS1CTSG | |
| SCHEMBL19827331 | 0.92 | MEN1 (0.53) | MEN1KMT2AASAH1PRSS1CTSG | |
| SCHEMBL15281659 | 0.85 | CNR2 (0.50) | MEN1KMT2APRSS1CTSGCTRB1 | |
| SCHEMBL17035837 | 0.84 | CNR2 (0.50) | MEN1KMT2ADEGS1CETPTHRB | |
| SCHEMBL17035830 | 0.83 | MEN1 (0.35) | MEN1KMT2AASAH1DEGS1 | |
| SCHEMBL17035836 | 0.83 | MEN1 (0.35) | MEN1KMT2AASAH1DEGS1 | |
| SCHEMBL17035854 | 0.82 | MEN1 (0.33) | MEN1KMT2AASAH1 | |
| SCHEMBL16588609 | 0.81 | MEN1 (0.43) | MEN1KMT2APRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2851092-A1 | Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2015-03-25 | — | — | EP | disclosed |