Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588745 | 0.96 | CYP2D6 (0.37) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL16588769 | 0.92 | CYP2D6 (0.32) | CYP2D6SMN1; SMN2CYP3A4 | |
| SCHEMBL16588839 | 0.86 | MCL1 (0.33) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL16588836 | 0.83 | MEN1 (0.33) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL16588742 | 0.82 | HTT (0.32) | KDM4E | |
| SCHEMBL16588879 | 0.82 | KDM4E (0.33) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL16588763 | 0.82 | CA1 (0.36) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL16588743 | 0.81 | CYP2D6 (0.36) | ALDH1A1MEN1KMT2ACYP2D6CYP3A4 | |
| SCHEMBL16588702 | 0.80 | MEN1 (0.35) | ALDH1A1MEN1KMT2AKDM4EATM | |
| SCHEMBL16588698 | 0.79 | CA1 (0.31) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | claimed |
| EP-2751142-B1 | POLYMERS FUNCTIONALIZED WITH LACTONES OR THIOLACTONES CONTAINING A PROTECTED AMINO GROUP | BRIDGESTONE CORP (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-8993683-B2 | Polymers functionalized with lactones or thiolactones containing a protected amino group | BRIDGESTONE CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |