Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592332 | 0.82 | ELANE (0.31) | ELANE | |
| SCHEMBL16562415 | 0.82 | GRM4 (0.31) | — | |
| SCHEMBL16592323 | 0.81 | CNR1 (0.34) | CNR1CNR2 | |
| SCHEMBL16592328 | 0.81 | CNR1 (0.36) | CNR1CNR2 | |
| SCHEMBL16562416 | 0.81 | — | — | |
| SCHEMBL16585701 | 0.81 | CNR1 (0.36) | CNR1CNR2 | |
| SCHEMBL16592324 | 0.79 | POLB (0.33) | POLBCNR1CNR2 | |
| SCHEMBL16562546 | 0.68 | CNR2 (0.32) | CNR2 | |
| SCHEMBL16562544 | 0.67 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL16562545 | 0.67 | CNR1 (0.33) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160219881-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL-PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2016-08-04 | — | — | US | disclosed |
| US-20160219881-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL-PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2016-08-04 | — | — | US | disclosed |
| WO-2015040114-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL-PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160219881-A1 | HERBICIDALLY ACTIVE 2-HALOGEN-4-ALKYNYL-PHENYL-PYRAZOLIDINE-DIONE OR PYRROLIDINE-DIONE DERIVATIVES | CBR3, CBR1, CNPY2 | POLB 3852/4885GAA 4107/4885NPSR1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.