Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592449 | 1.00 | GRM4 (0.65) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592470 | 1.00 | GRM4 (0.65) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30079805 | 1.00 | GRM4 (0.65) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592447 | 1.00 | GRM4 (0.65) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592417 | 0.91 | GRM4 (0.54) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592418 | 0.91 | GRM4 (0.54) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592439 | 0.91 | GRM4 (0.54) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592559 | 0.91 | GRM4 (0.54) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16592419 | 0.88 | GRM4 (0.56) | GRM4KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL16592420 | 0.88 | GRM4 (0.56) | GRM4KMT2AKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2853565-A1 | Glutamate receptor photomodulators | Consejo Superior De Investigaciones Científicas (ES) | 2015-04-01 | — | — | EP | disclosed |