⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18101853 | 0.74 | CYP2D6 (0.32) | — | |
| SCHEMBL294410 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL10728262 | 0.67 | — | — | |
| SCHEMBL21232974 | 0.67 | — | — | |
| Bromide SCHEMBL5507728 | 0.67 | — | — | |
| SCHEMBL21589372 | 0.65 | — | — | |
| SCHEMBL21779449 | 0.65 | — | — | |
| SCHEMBL12657780 | 0.65 | — | — | |
| SCHEMBL21102077 | 0.65 | — | — | |
| SCHEMBL18634640 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183331-A1 | MODIFIED TNF-ALPHA ANTIBODIES AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-06-15 | — | — | US | disclosed |
| EP-3925627-A1 | DRUG-CONJUGATES AND USES THEREOF | Concortis Biosystems, Corp (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2015039612-A1 | COMPOUND INHIBITING KINASE ACTIVITIES OF BTK AND/OR JAK3 | 北京韩美药品有限公司 | 2015-03-26 | — | — | WO | disclosed |