Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.61 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599700 | 1.00 | ITGB2 (0.61) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599917 | 0.93 | HDAC3 (0.57) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599731 | 0.93 | ITGB2 (0.72) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599729 | 0.93 | ITGB2 (0.72) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599922 | 0.92 | HDAC3 (0.56) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599925 | 0.92 | HDAC3 (0.56) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16609004 | 0.92 | ITGB2 (0.56) | ITGB2ICAM1ITGALHDAC3HDAC4 | |
| SCHEMBL16599755 | 0.91 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16599756 | 0.91 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16599777 | 0.91 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048306-A1 | NOVEL AGENTS TARGETING CYP51 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-04-02 | — | — | WO | disclosed |