⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19509618 | 0.69 | BLM (0.33) | — | |
| SCHEMBL209332 | 0.69 | — | — | |
| SCHEMBL8675218 | 0.69 | — | — | |
| SCHEMBL27660391 | 0.69 | — | — | |
| SCHEMBL27660388 | 0.69 | BLM (0.31) | — | |
| SCHEMBL18900801 | 0.69 | — | — | |
| Formamide SCHEMBL9479873 | 0.69 | MAPT (0.30) | — | |
| SCHEMBL14813248 | 0.67 | — | — | |
| SCHEMBL11002095 | 0.67 | — | — | |
| SCHEMBL7456117 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501022-A | Benzimidazole derivatives as cannabinoid receptor 1 receptor antagonists | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | CN | claimed |
| CN-101472917-A | Benzimidazole 5-sulfonamide derivatives as cannabinoid 1 (CB1) receptor ligands | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | claimed |
| WO-2015044928-A1 | SUBSTITUTED INDOLES AND THEIR USE AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | STELLENBOSCH UNIVERSITY (ZA) | 2015-04-02 | — | — | WO | disclosed |
| CN-101501022-A | Benzimidazole derivatives as cannabinoid receptor 1 receptor antagonists | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | CN | disclosed |
| CN-101472917-A | Benzimidazole 5-sulfonamide derivatives as cannabinoid 1 (CB1) receptor ligands | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | disclosed |