Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805589 | 0.92 | GRIN2B (0.67) | GRIN2B | |
| SCHEMBL30076199 | 0.86 | GRIN2B (0.66) | GRIN2B | |
| SCHEMBL24866070 | 0.84 | GRIN2B (0.59) | GRIN2BSIGMAR1 | |
| SCHEMBL16600797 | 0.79 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16608106 | 0.79 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL24866071 | 0.78 | GRIN2B (0.65) | GRIN2BSIGMAR1 | |
| SCHEMBL16608153 | 0.78 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601317 | 0.78 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL18629667 | 0.77 | GRIN2B (0.65) | GRIN2B | |
| SCHEMBL16608313 | 0.76 | GRIN2B (0.60) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036221-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Luc Therapeutics, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |