Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 0.67 |
| ▸ | MTOR | P42345 | 16/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.67 |
| ▸ | ABL1 | P00519 | 16/20 | 0.67 |
| ▸ | PRKDC | P78527 | 15/20 | 0.67 |
| ▸ | EGFR | P00533 | 14/20 | 0.67 |
| ▸ | HCK | P08631 | 14/20 | 0.67 |
| ▸ | KDR | P35968 | 14/20 | 0.67 |
| ▸ | EPHB4 | P54760 | 14/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.63 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.63 |
| ▸ | STK16 | O75716 | 1/20 | 0.63 |
| ▸ | STK10 | O94804 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.63 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607034 | 0.90 | SRC (0.67) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1785138 | 0.87 | SRC (0.62) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8008773 | 0.84 | SRC (0.59) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7997101 | 0.83 | SRC (0.69) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7997108 | 0.83 | SRC (0.57) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL1787523 | 0.83 | PIK3CD (0.62) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8012348 | 0.82 | SRC (0.56) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8012344 | 0.82 | PIK3CD (0.56) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8008776 | 0.82 | MTOR (0.57) | SRCMTORPIK3CDPIK3CAPIK3CB | |
| SCHEMBL19645242 | 0.82 | SRC (0.67) | SRCMTORPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993580-B2 | Benzothiazole kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2015-03-31 | — | — | US | disclosed |