SCHEMBL16601674

SCHEMBL16601674

CCc1cccc(CC)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1cccc(C(=O)O)c1)C3=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.58
MEN1 O00255 6/20 0.58
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 1/20 0.58
TYMS P04818 1/20 0.55
ANPEP P15144 2/20 0.53
DPP4 P27487 2/20 0.53
HSD17B10 Q99714 1/20 0.52
S100B P04271 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
POLB P06746 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CASP6 P55212 1/20 0.50
RXFP1 Q9HBX9 2/20 0.49
MAPK1 P28482 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 1/20 0.48
RECQL P46063 1/20 0.48
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601820 0.89 TYMS (0.56) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL14172750 0.87 KMT2A (0.72) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL16602052 0.81 KMT2A (0.70) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL22221562 0.81 ANPEP (0.66) KMT2AMEN1ALDH1A1KDM4EANPEP
SCHEMBL16601675 0.81 KMT2A (0.58) KMT2AMEN1ALDH1A1KDM4EANPEP
SCHEMBL14510327 0.80 KMT2A (0.64) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL5132896 0.80 KMT2A (0.64) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL5160880 0.79 KMT2A (0.63) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL5160901 0.79 KMT2A (0.63) KMT2AMEN1ALDH1A1KDM4ETYMS
SCHEMBL16601770 0.79 NPC1 (0.66) KMT2AMEN1ALDH1A1KDM4EANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11061341-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-07-13 US disclosed
US-20200041918-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed