Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601794 | 0.93 | BACE1 (0.70) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL21887173 | 0.84 | BACE1 (0.70) | BACE1PTPN1MAOAMAOBMEN1 | |
| SCHEMBL31423340 | 0.82 | BACE1 (1.00) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL312389 | 0.82 | BACE1 (1.00) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL16601727 | 0.82 | BACE1 (0.59) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL16601720 | 0.82 | BACE1 (0.59) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL16601785 | 0.81 | BACE1 (0.57) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL12112513 | 0.79 | MEN1 (0.61) | ESR1ESR2HSD17B1MAOAUGT1A1 | |
| SCHEMBL17208446 | 0.77 | BACE1 (0.47) | BACE1PTPN1MGAMGAASI | |
| SCHEMBL22220312 | 0.77 | BACE1 (0.68) | BACE1PTPN1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |