SCHEMBL16601987

SCHEMBL16601987

CCc1cccc(C)c1N1C(=O)c2cc(C#N)c3c4c(cc(C#N)c(c24)C1=O)C(=O)N(C(CC)CO)C3=O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.39
ANPEP P15144 4/20 0.39
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16602020 0.86 ANPEP (0.37) DPP4ANPEP
SCHEMBL16601636 0.86 DPP4 (0.41) DPP4ANPEPMEN1KMT2A
SCHEMBL24977904 0.83
SCHEMBL16601640 0.83 DPP4 (0.39) DPP4ANPEPMEN1KMT2A
SCHEMBL16656331 0.82 DPP4 (0.42) DPP4ANPEPMEN1KMT2A
SCHEMBL12629126 0.82 DPP4 (0.45) DPP4ANPEPMEN1KMT2A
SCHEMBL16601805 0.81 DPP4 (0.40) DPP4ANPEPMEN1KMT2A
SCHEMBL15764203 0.79 ANPEP (0.46) DPP4ANPEP
SCHEMBL16601651 0.78 ANPEP (0.35) DPP4ANPEPMEN1KMT2A
SCHEMBL15764232 0.78 DPP4 (0.42) DPP4ANPEPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed