Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 6/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | MARK3 | P27448 | 2/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | STK25 | O00506 | 1/20 | 0.48 |
| ▸ | CIT | O14578 | 1/20 | 0.48 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671171 | 1.00 | SYK (0.52) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL16606914 | 0.81 | SYK (0.48) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL16606932 | 0.79 | SYK (0.53) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL16606909 | 0.79 | SYK (0.53) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL1083288 | 0.79 | SYK (0.62) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL16606925 | 0.78 | SYK (0.81) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL16607004 | 0.77 | MARK3 (0.34) | SYKMARK3 | |
| SCHEMBL16606918 | 0.77 | MARK3 (0.32) | SYKMARK3 | |
| SCHEMBL22068257 | 0.76 | SYK (0.69) | SYKNTRK1NTRK3NTRK2ADORA3 | |
| SCHEMBL14235384 | 0.76 | SYK (0.49) | SYKNTRK1NTRK3NTRK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456720-B1 | NOVEL CRYSTALLINE SALT FORM OF 2,2-DIMETHYL-6-((4-((3,4,5-TRIMETHOXYPHENYL)AMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE FOR MEDICAL APPLICATION | LIMITED MOLECULAR TECH (RU) | 2021-06-30 | — | — | EP | disclosed |
| US-10745414-B2 | Crystal salt form of 2,2-dimethyl-6-((4-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazine-2-yl)amino)-2H-pyrido[3,2-b][1,4]oxazine-3(4H)-one for human use | LIMITED “MOLECULAR TECHNOLOGIES” (RU) | 2020-08-18 | — | — | US | disclosed |
| US-20190292198-A1 | A NEW CRYSTAL SALT FORM OF 2,2-DIMETHYL-6-((4-((3,4,5-TRIMETHOXYPHENYL)AMINO)-1,3,5-TRIAZINE-2-YL)AMINO)-2H PYRIDO[3,2-B][1,4]OXAZINE-3(4H)-ONE FOR HUMAN USE | LIMITED "MOLECULAR TECHNOLOGIES" (RU) | 2019-09-26 | — | — | US | disclosed |
| EP-3456720-A1 | NOVEL CRYSTALLINE SALT FORM OF 2,2-DIMETHYL-6-((4-((3,4,5-TRIMETHOXYPHENYL)AMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE FOR MEDICAL APPLICATION | Limited "Molecular Technologies" (RU) | 2019-03-20 | — | — | EP | disclosed |
| WO-2015047124-A1 | NOVEL CHEMICAL COMPOUNDS DERIVED FROM 2,4-DIAMINO-1,3,5-TRIAZINE FOR THE PROPHYLAXIS AND TREATMENT OF HUMAN AND ANIMAL DISEASES | Общество с ограниченной ответственностью "Молекулярные Технологии" | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745414-B2 | Crystal salt form of 2,2-dimethyl-6-((4-((3,4,5-trimethoxyphenyl)amino)-1,3,5-triazine-2-yl)amino)-2H-pyrido[3,2-b][1,4]oxazine-3(4H)-one for human use | SYK, SRC, JAK2 | SYK 1/4885NTRK1 285/4885NTRK3 633/4885 |
| US-20190292198-A1 | A NEW CRYSTAL SALT FORM OF 2,2-DIMETHYL-6-((4-((3,4,5-TRIMETHOXYPHENYL)AMINO)-1,3,5-TRIAZINE-2-YL)AMINO)-2H PYRIDO[3,2-B][1,4]OXAZINE-3(4H)-ONE FOR HUMAN USE | SYK, SRC, JAK1 | SYK 1/4885NTRK1 270/4885NTRK3 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.