SCHEMBL1660748

SCHEMBL1660748

[CH2]C1COCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37553 0.79
SCHEMBL19581786 0.77
SCHEMBL1133425 0.65
SCHEMBL27399 0.65
SCHEMBL1361148 0.65
Ethylene SCHEMBL11844746 0.65
SCHEMBL337298 0.64
SCHEMBL1863657 0.62
SCHEMBL107513 0.62
SCHEMBL23483170 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973768-B1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-07-09 EP claimed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP claimed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO claimed
EP-0138538-B1 2-DIOXACYCLOALKYLTHIOPENEM DERIVATIVES PFIZER INC. (US) 1988-12-14 EP claimed
CN-117120429-A KHK inhibitor 吉利德科学公司 2023-11-24 CN disclosed
EP-2487177-A1 PYRAZOLOXAZOLE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2012-08-15 EP disclosed
US-20110086898-A1 PYRAZOLOOXAZOLE COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-04-14 US disclosed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
US-6583164-B1 Lyophilized imidazole-1-yl or 1,2,4-triazole-1-yl quaternized with a alklycarbonyloxy alkyl group eliminated in vivo; a saccharide; 4-acetoxymethyl-1-(3-(2-oxo-3-(4-(1H-tetrazol-yl) phenyl)-1-imidazolydinyl)butyl)-1H-1,2,4-triazolium chloride TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-24 US disclosed
US-6407129-B1 INJECTABLE QUATERNIZED SALT FUNGICIDES; WATER SOLUBILITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
EP-1120116-A1 ANTIMYCOTIC DRUG COMPOSITION Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP disclosed
EP-0973768-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 2000-01-26 EP disclosed
WO-1998043970-A1 AZOLE COMPOUNDS, THEIR PRODUCTION AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-08 WO disclosed