Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 12/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16608472 | 0.91 | GRIN2B (0.73) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL18629468 | 0.84 | GRIN2B (0.66) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL16601310 | 0.84 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL30076049 | 0.84 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601307 | 0.84 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL16601305 | 0.84 | GRIN2B (1.00) | GRIN2B | |
| SCHEMBL9825127 | 0.80 | GRIN2B (0.66) | GRIN2BHTR1ADRD2HTR2AHTR2C | |
| SCHEMBL16608434 | 0.79 | GRIN2B (0.72) | GRIN2BGRIN1HTR1ADRD2HTR2A | |
| SCHEMBL8543338 | 0.79 | GRIN1 (0.64) | GRIN2BGRIN1HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL10682283 | 0.78 | GRIN2B (0.64) | GRIN2BHTR1ADRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |