Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25159572 | 0.90 | ADRB3 (0.68) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL6621610 | 0.86 | ADRB3 (0.70) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL15994158 | 0.86 | ADRB3 (0.70) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL16609338 | 0.85 | ADRB3 (0.69) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL21952232 | 0.85 | ADRB3 (0.69) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL28986806 | 0.84 | ADRB3 (0.68) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL31361990 | 0.84 | ADRB3 (0.68) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL28986807 | 0.84 | ADRB3 (0.68) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL16609237 | 0.80 | ADRB3 (0.62) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 | |
| SCHEMBL17209111 | 0.80 | ADRB3 (0.62) | ADRB3ADRB1ADRB2CYP2D6SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |