Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3449809 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL3451356 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL27442331 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL3451378 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL3449861 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL10484484 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL24755099 | 1.00 | EPHX1 (0.46) | EPHX1OPRM1TSHRALDH1A1SPHK1 | |
| SCHEMBL4657304 | 0.97 | — | — | |
| SCHEMBL18602905 | 0.90 | — | — | |
| SCHEMBL180063 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3380538-A1 | AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY | Sika Technology AG (CH) | 2018-10-03 | — | — | EP | disclosed |
| WO-2017089472-A1 | AMINE FOR CURABLE POLYMER COMPOSITIONS WITH HIGH PROCESS RELIABILITY | SIKA TECHNOLOGY AG (CH) | 2017-06-01 | — | — | WO | disclosed |
| WO-2015048819-A1 | ANTI-ALPHAVBETA1 INTEGRIN COMPOUNDS AND METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-02 | — | — | WO | disclosed |