SCHEMBL16610513

SCHEMBL16610513

CNc1ccccc1.C[SiH](C)C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.82
TDP1 Q9NUW8 5/20 0.45
ALDH1A1 P00352 4/20 0.45
HSD17B10 Q99714 4/20 0.45
CTSD P07339 1/20 0.45
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
AR P10275 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGS2 P35354 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
MAPK1 P28482 1/20 0.43
HTR2B P41595 1/20 0.43
KDM1A O60341 1/20 0.42
IDO1 P14902 2/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454 0.91
Benzene SCHEMBL17977991 0.91 TSHR (1.00) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL3008675 0.91
SCHEMBL19298582 0.91 TSHR (1.00) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL4675612 0.88
Phosphine SCHEMBL11220255 0.88 TSHR (0.93) TSHRTDP1ALDH1A1HSD17B10CTSD
SCHEMBL11220257 0.88 TSHR (0.93) TSHRTDP1ALDH1A1HSD17B10CTSD
Iodide SCHEMBL22092509 0.88
Ammonia Solution, Strong SCHEMBL7932140 0.88
Bromide SCHEMBL9803500 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857436-B1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORP (JP) 2019-10-09 EP disclosed
US-9969843-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2018-05-15 US disclosed
US-9803052-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2017-10-31 US disclosed
US-20170051108-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-23 US disclosed
US-20170044314-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-16 US disclosed
US-9505879-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2016-11-29 US disclosed
US-20150133622-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2015-05-14 US disclosed
EP-2857436-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME Kaneka Corporation (JP) 2015-04-08 EP disclosed