Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731837 | 0.87 | MEN1 (0.49) | MEN1KMT2AMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL16731574 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL1088391 | 0.78 | MEN1 (0.53) | MEN1KMT2AMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL16610727 | 0.78 | CYP17A1 (0.53) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL16610640 | 0.78 | CYP17A1 (0.53) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL16610643 | 0.78 | CYP17A1 (0.53) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL21466609 | 0.75 | EPHX2 (0.52) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4037135 | 0.74 | MEN1 (0.49) | MEN1KMT2AMAPTEPHX2SMN1; SMN2 | |
| SCHEMBL7797401 | 0.73 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2P2RX7 | |
| SCHEMBL3318267 | 0.73 | MEN1 (0.56) | MEN1KMT2AMAPTEPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857385-B1 | PRODRUG OF FLUORINE-CONTAINING AMINO ACID | TAISHO PHARMACEUTICAL CO LTD (JP) | 2017-08-02 | — | — | EP | disclosed |
| CN-104334524-B | The prodrug of fluorinated amino acids | 大正制药株式会社 | 2016-10-12 | — | — | CN | disclosed |
| US-9428483-B2 | Prodrug of fluorine-containing amino acid | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2016-08-30 | — | — | US | disclosed |
| US-20150141669-A1 | PRODRUG OF FLUORINE-CONTAINING AMINO ACID | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2857385-A1 | PRODRUG OF FLUORINE-CONTAINING AMINO ACID | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141669-A1 | PRODRUG OF FLUORINE-CONTAINING AMINO ACID | SLC1A2, SLC1A1, SLC1A3 | MEN1 2462/4885KMT2A 496/4885MAPT 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.