Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610809 | 0.90 | KDR (0.46) | KDR | |
| SCHEMBL16610971 | 0.87 | KDR (0.45) | KDRTRPC3TRPC6LCK | |
| SCHEMBL16610576 | 0.82 | KDR (0.44) | KDRTRPC3TRPC6 | |
| SCHEMBL18557099 | 0.81 | KDR (0.43) | KDR | |
| SCHEMBL16610520 | 0.81 | KDR (0.40) | KDRTRPC3TRPC6 | |
| SCHEMBL16610621 | 0.79 | KDR (0.40) | KDRTRPC3TRPC6 | |
| SCHEMBL18557040 | 0.79 | KDR (0.41) | KDR | |
| SCHEMBL16772706 | 0.78 | KDR (0.41) | KDRTRPC3TRPC6 | |
| SCHEMBL16610755 | 0.78 | KDR (0.41) | KDRTRPC3TRPC6 | |
| SCHEMBL16610670 | 0.77 | KDR (0.40) | KDRTRPC3TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857398-A1 | AROMATIC HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL | Nippon Shinyaku Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |