Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 7/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788175 | 0.88 | MAPK1 (0.51) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL12847886 | 0.87 | SRC (0.44) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL16612622 | 0.86 | MAPK1 (0.46) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL23069262 | 0.85 | CYP19A1 (0.47) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL15121329 | 0.85 | SRC (0.47) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL16033032 | 0.82 | GGPS1 (0.48) | MAPK1SRCEP300 | |
| SCHEMBL21063655 | 0.82 | SRC (0.44) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL12792742 | 0.82 | SRC (0.42) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL14104171 | 0.81 | SRC (0.43) | MAPK1SRCMAPK14PKMATM | |
| SCHEMBL908777 | 0.81 | MAPK1 (0.50) | MAPK1SRCMAPK14PKMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |