Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | EBP | Q15125 | 2/20 | 0.32 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703924 | 0.91 | KDM4E (0.39) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL883727 | 0.91 | PDE7A (0.35) | POLBKMT2AMEN1PDE7ACYP2C19 | |
| SCHEMBL724768 | 0.82 | POLB (0.40) | POLBKMT2AMEN1PDE7A | |
| SCHEMBL723913 | 0.82 | PDE7A (0.36) | POLBKMT2AMEN1PDE7A | |
| SCHEMBL12793878 | 0.81 | POLB (0.34) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL15685757 | 0.81 | POLB (0.34) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL12793873 | 0.81 | POLB (0.34) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL19853574 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL14175056 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL724860 | 0.80 | POLB (0.43) | POLBKMT2AMEN1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |