SCHEMBL16612468

SCHEMBL16612468

NC(=O)CN(CCCCO)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
FABP5 Q01469 3/20 0.39
FABP7 O15540 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
EPHX2 P34913 1/20 0.38
CCR6 P51684 1/20 0.34
PAX8 Q06710 1/20 0.34
HSD17B10 Q99714 1/20 0.33
CASP3 P42574 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18515377 0.86 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL16209818 0.83 KMT2A (0.47) KMT2AFABP5FABP7CA1CA2
SCHEMBL14559049 0.81 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL20425219 0.81 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL23085379 0.81 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL30510292 0.81 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL25182936 0.81 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL20371103 0.81 KMT2A (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL31170925 0.80 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2
SCHEMBL831614 0.80 KMT2A (0.45) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3276003-B1 SINGLE-CHAIN NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION CONTROL ABILITY BONAC CORP (JP) 2022-07-20 EP disclosed
US-11142769-B2 Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability BONAC CORPORATION (JP) 2021-10-12 US disclosed
US-10238752-B2 Single-stranded nucleic acid molecule for regulating expression of gene having delivering function BONAC CORPORATION (JP) 2019-03-26 US disclosed
US-20180119151-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION REGULATING ABILITY BONAC CORPORATION (JP) 2018-05-03 US disclosed
EP-3276003-A1 SINGLE-CHAIN NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION CONTROL ABILITY Bonac Corporation (JP) 2018-01-31 EP disclosed
US-20170306325-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR REGULATING EXPRESSION OF GENE HAVING DELIVERING FUNCTION BONAC CORPORATION (JP) 2017-10-26 US disclosed
US-9663784-B2 Single-stranded nucleic acid molecule for regulating expression of gene having delivering function BONAC CORPORATION (JP) 2017-05-30 US disclosed
US-20150105443-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR REGULATING EXPRESSION OF GENE HAVING DELIVERING FUNCTION BONAC CORPORATION (JP) 2015-04-16 US disclosed
EP-2857513-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR REGULATING EXPRESSION OF GENE HAVING DELIVERING FUNCTION Bonac Corporation (JP) 2015-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180119151-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING DELIVERY FUNCTION AND GENE EXPRESSION REGULATING ABILITY ZFX, ZFR, SRRT KMT2A 1325/4885FABP5 1834/4885FABP7 1081/4885
US-11142769-B2 Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability ZFX, ZFR, SRRT KMT2A 1325/4885FABP5 1834/4885FABP7 1081/4885
US-10238752-B2 Single-stranded nucleic acid molecule for regulating expression of gene having delivering function ZFX, RPRD2, YBX1 KMT2A 1473/4885FABP5 1828/4885FABP7 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.