SCHEMBL16612900

SCHEMBL16612900

Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(OC(O)CCO)ccn45)cccc32)n1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9942810 0.91 CSF1R (0.88) CSF1R
SCHEMBL15312670 0.90 CSF1R (0.87) CSF1R
Hydrochloric Acid SCHEMBL15312662 0.90 CSF1R (0.86) CSF1R
SCHEMBL15312536 0.87 CSF1R (0.75) CSF1R
SCHEMBL9974446 0.86 CSF1R (0.76) CSF1R
SCHEMBL15312554 0.86 CSF1R (0.71) CSF1R
SCHEMBL15312661 0.85 CSF1R (0.74) CSF1R
SCHEMBL9941699 0.85 CSF1R (0.73) CSF1R
SCHEMBL20003247 0.85 CSF1R (0.72) CSF1R
SCHEMBL15312693 0.85 CSF1R (0.67) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651939-B1 SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1,2-a]PYRIDINE-3-CARBOXAMIDE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS ARRAY BIOPHARMA INC (US) 2015-04-08 EP disclosed