Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612956 | 0.84 | HCRTR2 (0.75) | HCRTR2HCRTR1 | |
| SCHEMBL12479314 | 0.84 | HCRTR2 (0.80) | HCRTR2HCRTR1 | |
| SCHEMBL12479637 | 0.82 | HCRTR2 (0.80) | HCRTR2HCRTR1 | |
| SCHEMBL12479765 | 0.81 | HCRTR2 (0.79) | HCRTR2HCRTR1 | |
| SCHEMBL12480061 | 0.81 | HCRTR2 (0.73) | HCRTR2HCRTR1 | |
| SCHEMBL12479175 | 0.80 | HCRTR2 (0.57) | HCRTR2HCRTR1 | |
| SCHEMBL16612875 | 0.80 | HCRTR2 (0.75) | HCRTR2HCRTR1 | |
| SCHEMBL17641373 | 0.79 | HCRTR2 (0.72) | HCRTR2HCRTR1 | |
| SCHEMBL16613059 | 0.77 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL1165878 | 0.75 | HCRTR2 (0.77) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675801-B1 | NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-04-08 | — | — | EP | disclosed |