Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.54 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19177419 | 1.00 | GRM2 (0.54) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610929 | 1.00 | GRM2 (0.54) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610556 | 1.00 | GRM2 (0.54) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610461 | 1.00 | GRM2 (0.54) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610571 | 0.96 | GRM2 (0.51) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610498 | 0.94 | GRM2 (0.51) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL16610463 | 0.90 | GRM2 (0.51) | GRM2GRM3ALDH1A1HPGDCYP19A1 | |
| SCHEMBL16610610 | 0.88 | GRM2 (0.50) | GRM2GRM3ALDH1A1HPGDCYP19A1 | |
| SCHEMBL16610573 | 0.88 | GRM2 (0.50) | GRM2GRM3EPHX1ALDH1A1HPGD | |
| SCHEMBL19177218 | 0.87 | GRM2 (0.49) | GRM2GRM3EPHX1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857385-A1 | PRODRUG OF FLUORINE-CONTAINING AMINO ACID | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |