Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 7/20 | 0.74 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614726 | 0.95 | F2RL1 (0.75) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL16598690 | 0.93 | F2RL1 (0.71) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL16614886 | 0.93 | F2RL1 (0.71) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL18169482 | 0.93 | F2RL1 (0.71) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL16614608 | 0.92 | F2RL1 (0.72) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL16598496 | 0.91 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1RORC | |
| SCHEMBL16614674 | 0.91 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1RORC | |
| SCHEMBL16614601 | 0.91 | F2RL1 (0.74) | F2RL1ACACBACACAHPGDKDM4E | |
| SCHEMBL16614677 | 0.91 | F2RL1 (0.74) | F2RL1ACACBACACAALDH1A1RORC | |
| SCHEMBL16614695 | 0.91 | F2RL1 (0.74) | F2RL1ACACBACACAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048245-A1 | IMIDAZOPYRIDAZINES USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-04-02 | — | — | WO | disclosed |