SCHEMBL16616035

SCHEMBL16616035

CCCCCCCCCC(OC)(OC)[SiH2]C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.42
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36
DNM1 Q05193 6/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EPHX1 P07099 1/20 0.35
GGPS1 O95749 3/20 0.34
FDPS P14324 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4944335 0.98 SMPD1 (0.39) SMPD1TSHRTHRBDNM1MEN1
SCHEMBL8849917 0.80
SCHEMBL16616204 0.80 SMPD1 (0.41) SMPD1TSHRTHRBDNM1MEN1
SCHEMBL2200426 0.80 SMPD1 (0.41) SMPD1TSHRTHRBDNM1MEN1
SCHEMBL4582470 0.71 SMPD1 (0.55) SMPD1TSHRTHRBGGPS1FDPS
SCHEMBL7523594 0.71 SMPD1 (0.55) SMPD1TSHRTHRBGGPS1FDPS
SCHEMBL19390709 0.70 TSHR (0.44) SMPD1TSHRTHRBGGPS1FDPS
SCHEMBL20819823 0.70 TSHR (0.44) SMPD1TSHRTHRBGGPS1FDPS
SCHEMBL38663510 0.70 TSHR (0.44) SMPD1TSHRTHRBGGPS1FDPS
SCHEMBL11253869 0.70 TSHR (0.44) SMPD1TSHRTHRBGGPS1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095029-A Molded article and curable composition 2026-05-26 CN disclosed
US-20260118791-A1 TONER CANON KK (JP) 2026-04-30 US disclosed
EP-4086705-B1 TONER CANON KK (JP) 2026-03-25 EP disclosed
EP-4012501-B1 EXTERNAL ADDITIVE FOR TONER, TONER AND IMAGE FORMING APPARATUS CANON KK (JP) 2026-02-11 EP disclosed
US-12487539-B2 Fine particle, external additive for toners, and toner CANON KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
US-20250355380-A1 TWO-COMPONENT DEVELOPER CANON KK (JP) 2025-11-20 US disclosed
US-20250334896-A1 EXTERNAL ADDITIVE FOR TONER AND TONER CANON KK (JP) 2025-10-30 US disclosed
US-20250334892-A1 FINE POWDER FOR TONER AND TONER CANON KK (JP) 2025-10-30 US disclosed
US-20250278034-A1 EXTERNAL ADDITIVE FOR TONER AND TONER CANON KABUSHIKI KAISHA (JP) 2025-09-04 US disclosed
US-12360470-B2 External additive for toner, toner and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2025-07-15 US disclosed
EP-3674800-A1 TONER AND METHOD FOR PRODUCING TONER CANON KABUSHIKI KAISHA (JP) 2020-07-01 EP disclosed
US-9645518-B2 Toner CANON KABUSHIKI KAISHA (JP) 2017-05-09 US disclosed
US-9632441-B2 Toner CANON KABUSHIKI KAISHA (JP) 2017-04-25 US disclosed
EP-2860584-B1 Toner CANON KK (JP) 2017-04-05 EP disclosed
US-20160378003-A1 MAGNETIC TONER, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-12-29 US disclosed
US-9529289-B2 Method for producing toner particles CANON KABUSHIKI KAISHA (JP) 2016-12-27 US disclosed
US-20150378274-A1 TONER CANON KABUSHIKI KAISHA (JP) 2015-12-31 US disclosed
US-20150378275-A1 METHOD FOR PRODUCING TONER PARTICLES CANON KABUSHIKI KAISHA (JP) 2015-12-31 US disclosed
EP-2860584-A1 Toner Canon Kabushiki Kaisha (JP) 2015-04-15 EP disclosed
US-20150099224-A1 TONER CANON KABUSHIKI KAISHA (JP) 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118791-A1 TONER MSR1, H1-2, TAAR1 SMPD1 1729/4885TSHR 165/4885THRB 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.